StudentShare
Contact Us
Sign In / Sign Up for FREE
Search
Go to advanced search...
Free

Toxicity of Compound in the Zebrafish Bioassay - Lab Report Example

Cite this document
Summary
The paper "Toxicity of Compound in the Zebrafish Bioassay" is a good example of a lab report on chemistry. For our UPenn gastroenterologist collaborator to test the toxicity of compound 2 in the zebrafish bioassay, we provided Dr. Porter with the compound. At the end, a certain research grouped challenged that they were in a position to isoflavone using AlCl3in dioxane…
Download full paper File format: .doc, available for editing
GRAB THE BEST PAPER98.8% of users find it useful
Toxicity of Compound in the Zebrafish Bioassay
Read Text Preview

Extract of sample "Toxicity of Compound in the Zebrafish Bioassay"

The paper "Toxicity of Compound in the Zebrafish Bioassay" is a good example of a lab report on chemistry. For Dr. Pack, our UPenn gastroenterologist collaborator, to test the toxicity of compound 2 in the zebrafish bioassay, we provided Dr. Porter with the compound.

At the end of the chemical reaction session, a certain research grouped challenged that they were in a position to isoflavone using AlCl3in dioxane. In this case, the group did not state any conditions for this reaction to take place. As such, I decided to optimize the reaction conditions starting with the model compound Chromanone. In this case, I mixed chromanone and AlCl3 in dioxane and then refluxed the content for 3 hours. Unfortunately, I did not obtain positive results and hence I was prompted to repeat the procedure. In this attempt, I decreased dioxane’s volume from 50 ml to 20 ml, used 10% of AlCl3, and I prolonged the reaction time from 3 hours to 12 hours. During the reaction, I monitored the proceeding using TLC. However, I did not obtain the intended products after several tests. In the third attempt, I changed most of the conditions and measured used in the first two trials. In this case, I used 0.500 gm of chromanone in 20 ml dioxane and 0.40 mg of AlCl3 which represents 10% of the starting material. I also reduced the frequency of monitoring to 2 hours. After the first two hours, the starting materials had completely disappeared. This indicated that I had optimized the TLC condition, by using different ratios of ethyl acetate and hexane. Then, I ran prep-TLC and I realized 4 different compounds. I then separated these 4 new products and conducted tests by NMR. However, the 4 compounds did not match the expected NMR spectrum of the desired product.
My failure in these experiments prompted me to carry out research in journals and other materials. In this case, I came across some work discussing ring opining reaction on isoflavanones. The source has indicated all the conditions and the details about the experiment. However, the source suggests that I should use LiAlH4 which is a hazardous chemical. We had training with Dr. West on pyrophoric materials and now we are fully prepared to do the reaction. Read More
Tags
Cite this document
  • APA
  • MLA
  • CHICAGO
(Toxicity of Compound in the Zebrafish Bioassay Lab Report - 1, n.d.)
Toxicity of Compound in the Zebrafish Bioassay Lab Report - 1. https://studentshare.org/chemistry/1886614-editing
(Toxicity of Compound in the Zebrafish Bioassay Lab Report - 1)
Toxicity of Compound in the Zebrafish Bioassay Lab Report - 1. https://studentshare.org/chemistry/1886614-editing.
“Toxicity of Compound in the Zebrafish Bioassay Lab Report - 1”. https://studentshare.org/chemistry/1886614-editing.
  • Cited: 0 times

CHECK THESE SAMPLES OF Toxicity of Compound in the Zebrafish Bioassay

The Presence of Fluoride in Water

… The paper 'The Presence of Fluoride in Water' is a perfect example of an environmental studies term paper.... The activities that are happening in the area of the industry, agriculture, and other commercial areas have resulted in a situation of chemicals being discharged to the environment and that getting accumulated in the soil sediments....
8 Pages (2000 words) Term Paper

Enzymatic and Non-Enzymatic Browning

… Enzymatic and non-enzymatic BrowningIntroductionThe process of changing into brown and in particular foodstuff is called browning.... In some instances, browning of food may be desirable in such cases like caramelization or undesirable in situation when Enzymatic and non-enzymatic BrowningIntroductionThe process of changing into brown and in particular foodstuff is called browning....
8 Pages (2000 words) Essay

Campaign of Tax for Australias Future

… The paper "Campaign of Tax for Australia's Future " is a perfect example of a case study on marketing.... A carbon tax is a form of taxing fuel users who emit carbon to the environment during production, distribution or use of fossil fuels based on their combustion emissions (Hoeller & Wallin 1991)....
11 Pages (2750 words) Case Study

Managing Strategic Risk

Formaldehyde (CH2O) is an organic compound and is the simplest of aldehydes.... Formaldehyde (CH2O) is an organic compound and is the simplest of aldehydes.... Therefore, this poses an environmental risk to the species habiting in the river because formaldehyde is hazardous due to its mobility, and endurance, aquatic toxicity as well as toxicity to vertebrates....
10 Pages (2500 words) Case Study

Analysis and Evaluation of the Deepwater Horizon Oil Spill

In addition, consideration of the nature and toxicity of the oil well is salient as the timing the spill has occurred is important relative to seasonal breeding, and bird and fish migration patterns.... … The paper "Analysis and Evaluation of the Deepwater Horizon Oil Spill" is an outstanding example of a management case study....
12 Pages (3000 words) Case Study

The Process of Solving the Challenges

… The paper "The Process of Solving the Challenges " is a perfect example of management coursework.... nbsp;In the world, people are living today, and people have challenges here and there and, therefore, solving problems becomes part of life.... Be it at home, school, or even workplace, challenges pop in and the only way is solving them out....
7 Pages (1750 words) Coursework

Intellectual Property Management on the Invention of New MRI Contrast Agent-Based on Nano Diamonds

… The paper "Intellectual Property Management on the Invention of New MRI Contrast Agent-Based on Nano Diamonds" is an outstanding example of a business essay.... Nanodiamonds possess admirable optical and mechanical properties.... In addition, they are considered non-toxic, which makes them apposite for use in the biomedical field....
6 Pages (1500 words) Essay
sponsored ads
We use cookies to create the best experience for you. Keep on browsing if you are OK with that, or find out how to manage cookies.
Contact Us